Mrs. Edward B. Mayer died suddenly last night at her home, 21 East Eighty-second Street. She was the former Miss Benita Rosalind Guggenheim, daughter of Mr. and Mrs. Benjamin Guggenheim. Her father was drowned in the Titanic disaster. Mrs. Mayer was married in May, 1919. Her husband served in France during the war as an instructor in aviation. She is survived by her husband, mother and two sisters. Arrangements for the funeral had not been made last night.