Miss Mary Natalie Wick was born in Youngstown, Ohio on 2 August 1880.

She was the daughter of Youngstown-native and iron magnate George Dennick Wick (b. 1854) and Cleveland-born Mary Caroline Chamberlain (b. 1861). Her parents had married in Cleveland on 1 October 1879 and Mary was their only child. Her father was president of assorted iron companies in various parts of Ohio. Her mother died on 2 March 1893 and her father was remarried on 10 June 1896 to Mary Peebles Hitchcock, also of Youngstown, and she gained a step-brother, George Dennick Jr, on 19 March 1897.

In the 1890s Mary, better known as Natalie, seemingly spent time in England and was prominent in local society there. By the time of the 1910 census Natalie was still unmarried and still living with her family in Youngstown.

Natalie's father George had been suffering from ill-health for several years and it was decided that a vacation to Europe might benefit his wellbeing and prevent him having to retire. Along with her father, step-mother Natalie and her cousin Caroline Bonnell, Natalie departed from Youngstown in February 1912. They spent time in Naples, Venice, Paris and lastly London. In France they met Washington Roebling and Stephen Weart Blackwell who would also be aboard the Titanic on the voyage home. The family boarded the Titanic at Southampton as first class passengers (joint ticket number 36928 which cost £164, 17s, 4d). Also joining them at Southampton was another in-law, Elizabeth Bonnell. She occupied cabin C7 with Caroline Bonnell.

Natalie and Caroline were in bed the night of the 14 April. After feeling the collision with the iceberg, they went up on deck. Caroline said to Natalie, "Well, thank goodness, Natalie, we are going to see our iceberg at last!" They found the sea "smooth as glass" and were amazed at the number of stars. Finding nothing wrong, they decided to return to their cabins when a crew member told them to go and put on their life belts. They went to the stateroom of George and Mary Wick to tell them that the Titanic had struck an iceberg. Mr Wick rebuked the suggestion. Later, a crewmember must have told them to put on their life preservers and go up on deck. There, they were met by Natalie and Caroline. Caroline went below to bring her aunt Elizabeth up on deck and then the Wicks and Bonnells waited. The women were placed into lifeboat 8. They drifted about for five hours in the cold before being rescued by the Carpathia.

Her stepbrother George and William F. Bonnell were among the family members that travelled to New York City to meet the Carpathia. When they applied for tickets to enter the restricted area, they found that dozens of reporters had already claimed tickets as family members.

Natalie was married in London in 1916 to Tom St Aubyn Barrett Lennard Nevinson (b. 7 February 1870), a London-native and colonel in the British Army  who had served in the Royal Artillery in Kent in the 1890s as a Lieutenant with George Octavius Shaw Pringle, the future husband of another Titanic survivor Gladys Cherry. Tom had previously been married but was widowed and had a son from that union. Natalie and Tom later had two daughters, the first of whom, Mary, was born in 1917. The family maintained homes in both England and in France.

Following the outbreak of war in Europe in 1939 Natalie, who had a house in San Rafael, France, fled from the continent in July 1940 on board the Saltersgate, a small English coal barge whose other occupants on that trip included famed writer Somerset Maugham.

In later years Natalie lived in Thursley near Godalming in Surrey. She died following surgery on 12 October 1944 and was at the time a resident of Stoneyhead Nursing Home, Hindhead, Surrey. She is buried in St Michael and All Angels Churchyard, Thursley, Surrey.

Her widower Tom was never remarried and later lived in Knightsbridge, London. He died there on 4 November 1951 and is buried with his wife.